Evaluation of Interaction of Some Quinolone Derivatives on RSK-4 Using a Theoretical Model

نویسندگان

چکیده

Prostate cancer is one of the leading causes death among men worldwide; Some data suggest that ribosomal S6 p90 kinase (RSK 1-4), which belongs to group highly conserved Ser/Thr kinases, has been related an increase in prostate levels. For this reason, aim study was evaluate theoretical interaction some quinolone derivatives (compounds 1-19) with RSK-4 using 6rv2 protein and RSK-14 inhibitor (LJH685) a docking model. The results showed quino

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ژورنال

عنوان ژورنال: Clinical Cancer Investigation Journal

سال: 2022

ISSN: ['2278-0513', '2278-1668']

DOI: https://doi.org/10.51847/wrql2guumm